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Ilya Tsimafeyeu Selected Research

alofanib

1/2017Alofanib, an allosteric FGFR2 inhibitor, has potent effects on ovarian cancer growth in preclinical studies.
1/2016Targeting FGFR2 with alofanib (RPT835) shows potent activity in tumour models.
1/2016Molecular Modeling, de novo Design and Synthesis of a Novel, Extracellular Binding Fibroblast Growth Factor Receptor 2 Inhibitor Alofanib (RPT835).

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Ilya Tsimafeyeu Research Topics

Disease

19Neoplasms (Cancer)
10/2022 - 10/2010
14Renal Cell Carcinoma (Grawitz Tumor)
01/2021 - 04/2011
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2022 - 01/2017
2Infections
11/2021 - 06/2020
2Ovarian Neoplasms (Ovarian Cancer)
01/2017 - 01/2016
1COVID-19
11/2021
1Pneumonia (Pneumonitis)
11/2021
1Urinary Bladder Neoplasms (Bladder Cancer)
10/2021
1Cholangiocarcinoma
10/2021
1Hypogonadism (Hypergonadotropic Hypogonadism)
01/2021
1Chronic Disease (Chronic Diseases)
01/2021
1Fatigue
01/2021
1Hypothyroidism
01/2021
1Virus Diseases (Viral Diseases)
06/2020
1Fibrosis (Cirrhosis)
06/2020
1Disease Progression
06/2020
1Chronic Hepatitis C
06/2020
1Hepatocellular Carcinoma (Hepatoma)
01/2020
1Necrosis
01/2017
1Ovarian Epithelial Carcinoma
01/2017
1Triple Negative Breast Neoplasms
01/2016
1Stomach Neoplasms (Stomach Cancer)
01/2016
1Melanoma (Melanoma, Malignant)
01/2016
1von Hippel-Lindau Disease (von Hippel Lindau Disease)
10/2015
1Clear-cell metastatic renal cell carcinoma
06/2012

Drug/Important Bio-Agent (IBA)

5Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2021 - 04/2011
5Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2021 - 04/2011
3Sunitinib (Sutent)FDA Link
01/2021 - 07/2013
3alofanibIBA
01/2017 - 01/2016
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2020 - 01/2020
2Tyrosine Kinase InhibitorsIBA
01/2019 - 09/2015
2AntibodiesIBA
12/2018 - 04/2011
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
09/2015 - 10/2010
2Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
01/2015 - 12/2013
1Gam-COVID-Vac vaccineIBA
11/2021
1VaccinesIBA
11/2021
1GemcitabineFDA Link
10/2021
1Cisplatin (Platino)FDA LinkGeneric
10/2021
1pazopanibFDA Link
01/2021
1Prostate-Specific Antigen (Semenogelase)IBA
01/2021
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2021
1testosterone undecanoateIBA
01/2021
1Testosterone (Sustanon)FDA Link
01/2021
1Hemoglobins (Hemoglobin)IBA
01/2021
1NivolumabIBA
06/2020
1Immune Checkpoint InhibitorsIBA
06/2020
1Phosphotransferases (Kinase)IBA
01/2020
1tyrosine receptor (receptor, tyrosine)IBA
01/2020
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020
1ErbB Receptors (EGF Receptor)IBA
01/2019
1Axitinib (AG 013736)IBA
01/2019
1Sorafenib (BAY 43-9006)FDA Link
01/2019
1PlatinumIBA
01/2017
1Proteins (Proteins, Gene)FDA Link
01/2017
1Cytotoxins (Cytolysins)IBA
01/2017
1Anaplastic Lymphoma KinaseIBA
01/2017
1Carboplatin (JM8)FDA LinkGeneric
01/2017
1Paclitaxel (Taxol)FDA LinkGeneric
01/2017
1Protein Isoforms (Isoforms)IBA
01/2016
1EverolimusFDA Link
09/2015
1TOR Serine-Threonine KinasesIBA
09/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2015
1Bevacizumab (Avastin)FDA Link
09/2015
1Pharmaceutical PreparationsIBA
01/2015
1Monoclonal AntibodiesIBA
12/2013
1Immunoglobulin G (IgG)IBA
12/2013
1InterferonsIBA
07/2013
1Capecitabine (Xeloda)FDA Link
06/2012
1ParaffinIBA
04/2011
1Formaldehyde (Formol)FDA Link
04/2011

Therapy/Procedure

9Therapeutics
10/2022 - 07/2013
3Drug Therapy (Chemotherapy)
10/2021 - 01/2017
3Radiotherapy
01/2020 - 01/2017
2Radiofrequency Ablation
07/2013 - 10/2010
1Mechanical Ventilators (Ventilator)
11/2021
1Cystectomy
10/2021
1Heterologous Transplantation (Xenotransplantation)
01/2017
1Traditional Medicine (Folk Remedies)
04/2014